Plant derived API
Plant extract ointments
Deavit oil solution 10 ml # 10107
Код АТХ: А11СВ 0
1 ml solution contains 30 000 IU retinol palmitate (Vitamin A), and 40 000 IU ergocalciferol (Vitamin D2). /1 ml solution = 35 drops/
For prophylaxis of rachitis, treatment of initial mild rachitic manifestations, in the combined therapy of moderate and severe forms of rachitis.
Dosage and administration:
For rachitis prevention – the doses of 500 - 1000 IU Vitamin D2 usually meet the daily needs of the child. In premature infants and infants born with low body weight, prevention should begin 8 days after delivery: 2000 IU in children with body weight up to 1 500 g upon delivery, and 1500 IU for 1500 - 2000 g body weight respectively.
Therapeutic doses for rachitis treatment: initial mild rachitis - 2000-4000 IU daily;
moderate rachitis - 4000-6000 IU; severe rachitis - 6000-10000 IU.
In conditions of hypofunction of thyroid gland – 250 000 IU daily dose .
Recommended daily doses: adults - 10-15 drops daily; nursed infants - 3-6 drops daily, and children 5-10 drops daily.
Hypersensitivity to the product; hypervitaminosis D and A; severe liver and renal diseases, generalized atherosclerosis and heart decompensation; severe calcium - phosphorus disbalance.
To be administered with caution in pregnancy and lactation due to the risk of fetal anomalies during prolonged administration of high doses of Vitamin D to the mother.
Concomitant administration with laxatives, cholestyramine, and sucralfate leads to Vitamin A and D deficiency, due to resorption disorders. Thyroxin reduces Vitamin A effects.
Oral contraceptives reduce plasma levels of Vitamin A and exhaust its stores; barbiturates and hydantoin anticonvulsants reduce Vitamin D effects. Vitamin D antagonizes the effects of calcitonin. Concomitant administration with calcium-containing products and thiazide diuretics increase the risk of hypercalcemia. In oral administration, Vitamin A reduces the effects of corticosteroids, whereas in dermal application it enhances their epithelia-stimulating effect.
The preparation is very well tolerated. Sometimes it may provoke fatigue, somnolence, lack of appetite, alopecia, menstrual disorders, allergy reactions. There are data of teratogenic effect of retinol in high doses. In very rare cases skin dystrophy, cortical hyperostosis, preliminary closure of long bone epiphyses and hyperthermia have been observed.
Vial containing 10 ml oral solution.
On doctor’s prescription.
Manufactured by Sopharma AD: www.sopharma.com
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